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London Metal Exchange (LME): aluminum stocks decreased by 2,500 tons, copper stocks decreased by 75 tons, nickel stocks decreased by 2,862 tons, lead stocks decreased by 2,250 tons, tin stocks were flat, and zinc stocks decreased by 1,300 tons.In the latest centralized purchase of sitagliptin tablets, the price dropped to less than 20 cents per tablet, with a drop of over 90%. The reporter learned at the scene of the tenth batch of drug centralized purchase that more than 30 companies bid for sitagliptin, which is known as the largest variety in this centralized purchase, including Huahai Pharmaceutical, Kelun Pharmaceutical, Zhengda Tianqing, tonghua dongbao, Zhejiang Pharmaceutical, Jiudian Pharmaceutical, Shiyao Ouyi, Chenxin Pharmaceutical and many other companies. Judging from the bidding results, the lowest bid price among enterprises has dropped below 0.2 yuan per piece, which is more than 90% lower than the limit price. Statistics show that in 2023, the sales of this product in the terminals of public medical institutions in China exceeded 2 billion yuan, and the sales of Merck, the original research manufacturer, accounted for more than 90%, so there is a large room for generic drug substitution. The quotation of Meradong in this collection is about 7.37 yuan per piece. (science and technology innovation board Daily)The State Council agrees in principle with the Master Plan of Fuzhou Land and Space (2021-2035), and the State Council agrees in principle with the Master Plan of Fuzhou Land and Space (2021-2035) approved by the Ministry of Natural Resources. By 2035, the cultivated land in Fuzhou will be no less than 1,421,300 mu, of which the permanent basic farmland protection area will be no less than 1,267,200 mu; The red line area of ecological protection is not less than 5082.05 square kilometers, of which the red line area of marine ecological protection is not less than 2671.73 square kilometers; The border area of urban development is controlled within 1000.63 square kilometers; The use area of construction land per unit GDP decreased by not less than 40%; The retention rate of natural coastline on the mainland is not lower than the tasks assigned by the higher authorities, of which it will be not lower than 40.31% in 2025; The total water consumption shall not exceed the indicators issued by the higher authorities, including 2.80 billion cubic meters in 2025; Except for major national projects, reclamation is completely prohibited; Strictly manage uninhabited islands. Clarify the key prevention and control areas of natural disaster risks, delimit risk control lines such as floods and earthquakes, as well as green space system lines, water body protection lines, historical and cultural protection lines and infrastructure construction control lines, and implement safety guarantee spaces such as strategic mineral resources.

The monkeypox vaccine with independent intellectual property rights in China was approved for clinical use. On December 10th, the monkeypox vaccine jointly developed by China Bio-Beijing Institute of Biological Products and China Center for Disease Control and Prevention received the approval notice of drug clinical trial issued by National Medical Products Administration, and it was registered and classified as Class 1.2 innovative vaccine. The vaccine is an innovative vaccine independently developed by scientists in China with completely independent intellectual property rights, which is expected to play an important role in the prevention and control of diseases caused by monkeypox virus in China. (China Biology)Dagang shares: the bankruptcy proceedings of China University of Science and Technology Port have ended, and Dagang shares announced that the bankruptcy proceedings of Jiangsu University of Science and Technology Port Laser Technology Co., Ltd., a holding subsidiary of the company, have ended. Since the bankruptcy administrator took over the port of China University of Science and Technology, it is no longer included in the scope of the company's consolidated statements.EU finalizes new sanctions against Russia: strike against the "shadow fleet". According to a report on the website of German newspaper Sü ddeutsche Zeitung on December 11th, EU countries have reached an agreement on a new package of sanctions against Russia. Several diplomats told DPA that the new sanctions were aimed at strengthening the crackdown on the so-called "Russian shadow fleet" transporting oil and petroleum products. It is reported that more than 50 ships will be banned from entering EU ports. In addition, they can no longer get the services of EU enterprises. In June this year, the EU has taken preliminary measures to blacklist more than 20 Russian ships. It is reported that this is the 15th package of sanctions against Russia drawn up by the EU so far. The plan also stipulates that trade with more than 30 other business entities should be restricted, and the EU has determined that they should keep in touch with the Russian defense and security departments. In addition, the EU also plans to impose an entry ban and asset freeze on some individuals. According to the report, senior EU officials are pleased that member States have reached a consensus on this. Kaya Karas, the EU's High Representative for Foreign Affairs and Security Policy, said: "This will further weaken (Russian President) Putin's war machine." Roberta Metsola, Speaker of the European Parliament, said: "This sends another strong signal: our support for Ukraine will not weaken." The sanctions plan will be officially confirmed at the meeting of foreign ministers of member States in Brussels on the 16th, and then will be published in the official gazette of the European Union and come into effect. (Reference message)

The RMB exchange rate is expected to appreciate again at the end of the year. The research team of the Financial Market Department of Agricultural Bank of China said that the market transactions have shown obvious narrative-driven characteristics in recent years. Considering some recent changes, the RMB exchange rate is expected to stabilize and rebound again in the future. First, the pricing of Trump transactions in the international market has come to an end. Second, there has been a major shift in domestic macro policies. Since late September, financial policies such as lowering the RRR, cutting interest rates, supporting the stock market and the real estate market, and fiscal debt measures have boosted market confidence. Third, there has been a favorable change in supply and demand in the domestic foreign exchange market. The end of the year is the traditional peak season for enterprises to settle foreign exchange, and the continuous forward discount will lead to the backlog of foreign exchange settlement, which will further amplify the demand for foreign exchange settlement at the end of the year. Further considering the overall situation of the game between China and the United States, Trump's return not only means the enhancement of external shocks, but also the upgrading of internal policies. The RMB exchange rate will maintain two-way fluctuations next year, and it is no longer a steady profit for enterprises to hold US dollars and postpone foreign exchange settlement. While stabilizing domestic foreign trade and foreign investment, continuing to expand high-level opening-up and expanding domestic demand in an all-round way implies the certainty of economic stabilization and recovery, which is expected to promote the return of short-term securities investment and medium-and long-term direct investment and help the RMB stop falling and rebound.The full implementation of the personal pension system may bring more medium and long-term funds, and the allocation value of the Southern Shanghai and Shenzhen 300ETF(159925) has attracted much attention. On December 12, the Southern Shanghai and Shenzhen 300ETF(159925) closed up 1.07%, with a turnover of 92.5438 million yuan. The constituent stocks were all red, with Contemporary Amperex Technology Co., Limited rising by 2.47%, Kweichow Moutai rising by 1.97% and Wuliangye rising by 1.62%. China Merchants Bank and China Ping An followed suit. In the news, since December 15th, the personal pension system has been extended to the whole country, and the first batch of 85 index funds have been included in the product range, which has attracted attention, including 12 Shanghai and Shenzhen 300 index funds and 300ETF(159925) in South China. According to industry insiders, since the personal pension fund system came into being, both personal pension funds and sales organizations have steadily expanded. The increase of fund products and the continuous addition of new sales organizations will bring more medium and long-term funds to the capital market, and the Southern CSI 300ETF(159925) will benefit in the medium and long term.London Metal Exchange (LME): aluminum stocks decreased by 2,500 tons, copper stocks decreased by 75 tons, nickel stocks decreased by 2,862 tons, lead stocks decreased by 2,250 tons, tin stocks were flat, and zinc stocks decreased by 1,300 tons.